To be honest, I don’t quite understand that product…as boud said, it has a slightly (well…I’d say more than slightly, actually) dated 65W desktop CPU, I’ve only found one review but apparently it has a quite noisy fan, it’s always audible and at higher load ramps up a lot.
Also, this thing is not a mobile device either, it doesn’t have a battery at all, and seems too heavy to not use it on a desk anyway, so it’s strictly a desktop device, and as such, there’s only disadvantages of putting the actual computer inside the tablet device.
There are very compact systems like intel NUC and “clones”, or you may already have a laptop with similar if not better performance, neither really takes a lot of extra space compared to that huge screen.
Also, the review confirms, 1920x1080 at 22" is definitely not state of the art, you ARE seeing all of the pixels clearly, you can already see them at the usual monitor distance but work quite a bit closer in a tablet mode.
If I were to spend that amount of money, the Kamvas Pro 24 with its 2560x1440 display would appeal me more.