Yeah so, this is what both I and Wakocima have been talking about all along. Yes, I do recommend reading up on those older threads because there is a long history of people trying to implement Pigment-esque color mixing, which again, is not what I’m asking for in this suggestion.
You can forget about MixBox because it’s a paid/licensed product that can’t be incorporated into Krita. The Rebelle painting program uses it to great success though.
MixBox was based on Kubelka-Munk theory of color mixing, and some attempts were made to replicate this process in Krita. I believe Ronald van Wijnen had a working build of Krita that incorporated this, but there were some technical issues leading to it not being implemented in the long run.
Edit: Yes, I know about MyPaint. This is also why I mentioned in the OP that maybe we can utilize the MyPaint brush engine infrastructure to achieve the hue shift I’m talking about. In Krita.