There was a time when I used to be very dependant on MSEX5/CSP and it’s a very good software,but once I got over the addiction of those inbuilt 3d models,I gradually moved towards the free software like Medibang pro and Firealpaca.
For last two years I have been using them for full length professional comics work and illustrations,with very satisfying results.
These softwares are lightweight,very fast,quite easy to use , very professional and comes with regular support !
To be honest,if we can keep the 3d model part aside,these free softwares are 70-75 % close to most of the options available in CSP and gets updated with fix, new features,new set of brushes, at least 3-4 times a year.
Just wanted to share my experience,that’s all 
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